Scientific Programme

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  • Friday 26 February 2021


  • Saturday 27 February 2021


  • Sunday 28 February 2021


  • Welcome from Professor Siegfried Kasper, CINP President
    Presentation of Pioneer Awards to Judith L. Rapoport, Oleh Hornykiewicz and Torgny Svensson by Professor Siegfried Kasper, CINP President
    Pioneer Awardee Video (Judith Rapoport)
    Presentation of Brain Health Clinical Research Awardee by Professor Elias Eriksson, Chair Awards Committee and Professor Siegfried Kasper CINP President
    Clinical Research Awardee Video (Gustavo Turecki)
    Presentation of Brain Health Basic Research Awardee by Professor Elias Eriksson, Chair Awards Committee and Professor Siegfried Kasper CINP President
    Basic Research Awardee Video (Tibor Harkany)
    Presentation of Ethics Prize Winner by Professor Shih-Ku Lin, Chair Ethics Committee
    Ethics Prize Winner Video (Paul Appelbaum)
    Presentation of Max Hamilton Memorial Prize Winner by Professor Siegfried Kasper, CINP President
    Max Hamilton Memorial Prize Winner Video (Mu-Hong Chen)
    Presentation of Rafaelsen Young Investigators Awardees by Professor Pierre Blier, CINP President Elect
    Presentation of Student Encouragement Awardees by Professor Elias Eriksson, Chair Awards Committee
    Professor Siegfried Kasper declares the CINP Virtual Congress open

  • Chair: Shih-Ku Lin, Taiwan and Rupert Lanzenberger, Austria

    From Genes to Clinical Phenotype in ADHD Across the Lifespan
    Barbara Franke, Radboud University, The Netherlands
    Plenary Lecture

  • Chair: Georg S. Kranz, Hong Kong and Eileen Lueders, New Zealand

    1. Hormonal Treatment Effects on the Brain: Findings From the Enigma Transgender Persons Working Group
    Sven C. Müller, Belgium

    2. Sex Matters - A Multivariate Pattern Analysis of Sex and Gender
    Pia Baldinger-Melich, Austria

    3. Effects of Sex Hormones on Serotonergic Neurotransmission
    Georg S. Kranz, Hong Kong

    4. A New Theory About the Neurobiology of Gender Dysphoria
    Sarah M. Burke, The Netherlands
    Symposium

  • Next Generation Seizure Therapy and Neuromodulation, 新世代痙攣療法與神經調節
    Chair: Cheng-Ta Li, Taiwan

    1. Treatment Resistant Depression (TRD) and Theta Burst Stimulation (TBS)
    Cheng-Ta Li, Taiwan

    2. Therapeutic Mechanism of Theta-Burst Stimulation in an Antidepressant-Resistant Depression Rat Model
    Lin Hui-Ching, Taiwan

    3. Development of Precision Seizure Therapy for Treatment of Depression
    Zhi-De Deng, USA

    4. Application of tDCS for Pharmacology Research
    Kuo Hsiao-I, Taiwan
    Mandarin Session

  • Chair: Brian Dean, Australia and Wen-Sung Lai, Taiwan

    1. Evidence Suggesting the Muscarinic M1 Receptor Has a Role in the Aetiology and Treatment of Schizophrenia
    Brian Dean, Australia

    2. The Role of CHRM1 Signalling in Cognitive and Behavorial Symptoms of Psychosis
    Geor Bakker, The Netherlands

    3. Systems Biology of Mammalian Sleep/Wake Cycles: The Roles of Muscarinic Acetylcholine Receptor in NREM and REM Sleep
    Hiroki Ueda, Japan

    4. The Muscarinic M1 Receptor in CNS Function and as a Drug Target for Slowing the Progression of Neurodegenerative Disease
    Andrew Tobin, United Kingdom
    Symposium

  • Chair: Tian Mei Si, China and Konstantinos Fountoulakis, Greece

    1. Diagnosis
    Joseph Zohar, Israel

    2. Therapeutics
    Naomi Fineberg, United Kingdom
    Clinical Focus & Frontiers

  • Brain Images in Child and Adolescent, 兒童與青少年腦影像學
    Chair: Susan Shur-Fen Gau, Taiwan

    1. Imaging Endophenotype, Genetics, and Pharmacotherapy in ADHD
    Susan Shur-Fen Gau, Taiwan

    2. Cerebral Volumetric Correlates of ADHD Trait and Their Heritability: A Voxel-Based Morphometry Study of the ABCD data
    Chiang-Shan Ray Li, USA

    3. The NIMH Longitudinal Study of the Neurobiologic and Endocrine Events of Puberty: Hormonal and Metabolic Changes that Accompany Puberty in Typically Developing Children
    Shau-Ming Wei, USA

    4. Gray Matter Volumetric Correlates of Impulsivity in Children: An Adolescent Brain Cognition Development Project
    Chiang-Shan Ray Li, USA
    Mandarin Session

  • Chair: Noriko Osumi, Japan and Masanari Itokawa, Japan

    1. Cannabinoid Receptor Genetics: From Genes to Behavior and Neuro-Immune Crosstalk in Depression and Schizophrenia
    Emmanuel Onaivi, William Paterson University, USA
    Hiroki Ishiguro, University of Yamanashi, Japan
    Y. Horiuchi, Tokyo Metropolitan Institute, Japan
    Q.-R. Liu, TNIA-IRP/NIH, USA

    2. Cerebral Volumetric Correlates of ADHD Trait and Their Heritability: A Voxel-Based Morphometry Study of the ABCD Data
    Chiang-Shan Li, Yale University School of Medicine, USA

    3. Prominent Memory Deficits and Brain Beta-Amyloid Deposits in Elderly Treatment-Resistant Depression
    Hsuan Lee, Taipei Veterans General Hospital, Taiwan
    J.S. Jeng, Taipei Veterans General Hospital, Taiwan
    T.P. Su, National Yang-Ming University, Taiwan
    Y.M. Bai, Taipei Veterans General Hospital and National Yang-Ming University, Taiwan
    C.M. Cheng, Taipei Veterans General Hospital, Taiwan
    C.T. Li, Taipei Veterans General Hospital, National Yang-Ming University and National Central University, Taiwan

    4. Polygenetic Risk Scores for Major Psychiatric Disorders Among Schizophrenia Patients, Their First Degree Relatives and Healthy Subjects
    Kazutaka Ohi, Gifu University Graduate School of Medicine, Japan
    D. Nishizawa, Tokyo Metropolitan Institute of Medical Science, Japan
    T. Shimada, Kanazawa Medical University, Japan
    Y. Kataoka, Kanazawa Medical University, Japan
    J. Hasegawa, Tokyo Metropolitan Institute of Medical Science, Japan
    T. Shioiri, Gifu University Graduate School of Medicine, Japan
    Y. Kawasaki, Kanazawa Medical University, Japan
    R. Hashimoto, National Center of Neurology and Psychiatry, Japan
    K. Ikeda, Tokyo Metropolitan Institute of Medical Science, Japan

    5. The Differential Pattern of Functional and Structural Connectivity of Frontostriatal Circuits Between Methamphetamine Users With And Without Persistent Psychosis in Comparison to Patients with Schizophrenia
    Ming-Chyi Huang, College of Medicine, Taipei Medical University, Taiwan
    C.-W. Li, Wang-Fang Hospital, Taipei Medical University, Taiwan
    W. Chen, Wang-Fang Hospital, Taipei Medical University, Taiwan

    6. The Impact of Sex Hormones and Hormonal Contraception on D-amphetamine-Induced Dopamine Release: A [11C]-(+)-PHNO Study in Healthy Female Subjects
    Ana Weidenauer, Medical University of Vienna, Austria
    U. Sauerzopf, Medical University of Vienna, Austria
    I. Graf, Medical University of Vienna, Austria
    M. Bauer, Medical University of Vienna, Austria
    L. Bartova, Medical University of Vienna, Austria
    C. Philippe, Medical University of Vienna, Austria
    N. Berrotéran-Infante, Medical University of Vienna, Austria
    V. Pichler, Medical University of Vienna, Austria
    M. Mitterhauser, Medical University of Vienna, Austria
    W. Wadsak, Medical University of Vienna, Austria
    R. Lanzenberger, Medical University of Vienna, Austria
    S. Kasper, Medical University of Vienna, Center for Brain Research, Department of Molecular Neuroscience, Austria
    N. Praschak-Rieder, Medical University of Vienna, Austria
    M. Willeit, Medical University of Vienna, Austria
    Free Communication Session

  • Ketamine: The Good and The Bad, 愷他命:好處與壞處
    Chair: Tung-Ping Su, Taiwan

    1. Selecting DNA Methylation Features to Identify Substance Misuse
    Ke Xu, USA

    2. Psychological Consequence of Ketamine Abuse
    Ming-Chyi Huang, Taiwan

    3. Target and Mechanisms of Therapeutic and Dissociative Side Effects of Ketamine and Esketamine at Their Antidepressant Doses
    Guang Chen, USA

    4. Anti-Suicidal Effect of Single and Repeated Low Dose Ketamine Infusion in Patients with Treatment Resistant Depression (TRD) in Taiwan
    Tung-Ping Su, Taiwan
    Mandarin Session

  • Chair: William E. Bunney, United States and Po-Hsiu Kuo, Taiwan

    1. Abnormal Core Clock Genes in MDD: Potential Resetting with Rapid-Acting Antidepressants
    William E. Bunney, United States

    2. Strengthening of Circadian Rhythm Amplitude Stabilizes and Improves Mood: Evidence from Animal Models
    Colleen A. McClung, United States

    3. Adjustment of Central and Peripheral Circadian Clocks in Humans
    Diane B. Bolvin, Canada

    4. Light Signaling Alterations and Light Use in Depression
    Pierre A. Geoffroy, France
    Symposium

  • Chair: Steven Potkin, United States and Tetsuro Kikuchi, Japan

    1. Pharmalogical and Physiological Profiles of Aripiprazole, Brexpiprazole, and Cariprazine
    Pierre Blier, Canada

    2. Clincial Effects of Long-Acting Injectable Aripiprazole in Schizophrenia
    Steve Potkin, United States

    3. The Role of Brexpiprazole in the Treatment of Inadequate Response in Major Depressive Disorder
    Diane McIntosh, Canada

    4. Broad Spectrum Efficacy of Cariprazine in the Management of Bipolar Disorder
    Lakshmi Yatham, Canada
    Symposium

  • Chair: Siegfried Kasper, Austria and John Krystal, USA

    ACE2 – From Discovery to the Centre of a Pandemic
    Josef Penninger, Life Sciences Institute, University of British Columbia, Canada
    Plenary Lecture

  • Chair: Winston Shen, Taiwan and Toshi A. Furukawa, Japan

    Big Data Analyses for Neuropsychopharmacology: Harnessing Big Data Gives Rise to Evidence of a Common Neural Substrate Across Major Psychiatric Disorders
    Tung-Ping Su, Cheng-Hsin General Hospital, Taiwan
    Plenary Lecture

  • Chair: Siegfried Kasper, Austria and Tung-Ping Su, Taiwan

    1. Characterization of Treatment Resistant Depression in Europe
    Siegfried Kasper, Austria

    2. Genetic Findings in TRD
    Chiara Fabbri, Italy

    3. Glutamateric Approach in TRD
    Carlos Zarate, United States

    4. Deep Brain Stimulation in TRD
    Thomas Schläpfer, Germany
    Symposium

  • Psychopharmacoepidemiology, 精神藥物流行病學
    Chair: Chi-Shin Wu, Taiwan

    1. Risks and Benefits of ADHD Medication: Real-World Evidence from Pharmacoepidemiology Studies
    Zheng Chang, Sweden

    2. Cross-National Multi-Database Studies for Psychiatric Medication Safety
    Chia-Cheng Lai, Taiwan

    3. Comparative Effect of Antipsychotics on Risk of Self‐Harm Among Patients with Schizophrenia
    Chia-Hao Ma, Taiwan

    4. Associations Between Antidepressant Usage and Advanced Diabetes Outcomes in Patients with Depression and Diabetes Mellitus
    Shi-Heng Wang, Taiwan
    Mandarin Session

  • Chair: David Nutt, United Kingdom, Rupert Lanzenberger, Austria

    1. 5-HT Reuptake Site, 5-HT1A Receptors, and the Neuroimaging Revolution with Functional PET Providing High Temporal Resolution
    Rupert Lanzenberger, Austria

    2. Mu-opioid Receptor Availability and Functional Connectivity During Reward Processing in Gambling Disorder
    Chen-Chia Lan, Taiwan

    3. Dopamine D2 Receptors: Simultaneous PET Measures and fMRI Signals
    Christin Sander, United States

    4. 5-HT2A Receptor PET, Serotonin Release and Amygdala fMRI Responses in Depression
    David Nutt, United Kingdom
    Symposium

  • Chair: Elias Eriksson, Sweden and Pierre Blier, Canada

    1. The Clinical Impact of Melancholic Features in Major Depressive Disorder - Results From a Cross-Cectional European Multicenter Study
    Lucie Bartova, Medical University of Vienna, Austria
    M. Dold, Medical University of Vienna, Austria
    G. Fugger, Medical University of Vienna, Austria
    A. Kautzky, Medical University of Vienna, Austria
    A. Weidenauer, Medical University of Vienna, Austria
    U. Sauerzopf, Medical University of Vienna, Austria
    M. Mitschek, Medical University of Vienna, Austria
    R. Frey, Medical University of Vienna, Austria
    C. Fabbri, University of Bologna, Italy
    S. Montgomery, Imperial College, United Kingdom
    J. Zohar, Chaim Sheba Medical Center, Israel
    D. Souery, Université Libre de Bruxelles and Psy Pluriel, Centre Européen de Psychologie Médicale, Belgium
    J. Mendelwicz, Université Libre de Bruxelles and Psy Pluriel, Centre Européen de Psychologie Médicale, Belgium
    A. Serretti, University of Bologna, Italy
    S. Kasper, Medical University of Vienna, Center for Brain Research, Department of Molecular Neuroscience, Austria

    2. Investigating the Role of Genes Encoding the Fatty Acid Amide Hydrolase (FAAH) and Monoacylglyercide Lipase (MAGL) Enzymes in Emotional Processing in Adolescents
    Chandni Hindocha, University College London, United Kingdom
    H. Irizar, University College London, United Kingdom
    G. Schumann, King's College, London, United Kingdom

    3. Early Pup Removal Precipitates a Depressive-like State and Dopamine Deficit in Postpartum Rats: Amelioration by Social Support
    Millie Rincon Cortes, University of Pittsburgh, United States
    A. Grace, University of Pittsburgh, United States

    4. Translating Gene Networks into Treatments for Alzheimer's Disease
    Zachary Gerring, QIMR Berghofer Medical Research Institute, Australia
    E. Gamazon, Vanderbilt Genetics Institute, United States
    A. White, QIMR Berghofer Medical Research Institute, Australia
    E. Derks, QIMR Berghofer Medical Research Institute, Australia

    5. Meta-Analysis of Gray Matter Volume Changes After Electroconvulsive Therapy in Depression – An Update
    Pia Baldinger-Melich, Medical University of Vienna, Austria
    G. Grylewski, Medical University of Vienna, Austria
    S. Kasper, Medical University of Vienna, Center for Brain Research, Department of Molecular Neuroscience, Austria
    R. Frey, Medical University of Vienna, Austria
    R. Lanzenberger, Medical University of Vienna, Austria

    6. Computational Drug Repositioning for Psychiatric Disorders
    Hon-Cheong So, The Chinese University of Hong Kong, Hong Kong PRC
    Rafaelsen Symposium

  • Schizophrenia and Depression Research: State-of-the-Art Knowledge and the Future, 思覺失調症與重鬱症研究新知
    Chair: Yuan-Hwa Chou, Taiwan

    1. Future of Psychiatry: Role of Technology
    Xin-Min Li, Canada

    2. Alternative Treatments in Major Depression: Light Therapy and Exercise
    Yanbo Zhang, Canada

    3. Current Status of Pharmacological Treatment in Schizophrenia
    Yuan-Hwa Chou, Taiwan

    4. Pipeline Medications for Schizophrenia
    Shih-Ku Lin, Taiwan
    Mandarin Session

  • Chair: Joseph Zohar, Israel and Gabriella Gobbi, Canada

    1. Neurobiological Research in ADHD - Opportunities For Personized Medicine
    Barbara Franke, The Netherlands

    2. ADHD and Comorbities: Treatment Implications
    Larry Klassen, Canada
    Clinical Focus & Frontiers

  • Stress and Resilience, 壓力與彈韌
    Chair: Po See Chen, Taiwan

    1. Stress and Resilience
    Po See Chen, Taiwan

    2. KCNQ Channels in Stress Resilience: From the Preclinical Model to the Patient
    Ming-Hu Han, USA

    3. The Effect of Resilience on Suicide Attempt in High Risk Individuals
    Po-Hsiu Kuo, Taiwan
    Mandarin Session

  • Chair: Pierre Blier, Canada and Cheng-Ta Li, Taiwan

    1. Impact of Ketamine on the Intracellular Signaling Beyond the N-methyl-D-aspartate Receptors
    Lisa Monteggia, United States

    2. Neural Networks Involved in the Action of Ketamine
    Carlos Zarate, United States

    3. Impact of Intravenous Ketamine on Depression and Suicidal Ideation
    Jennifer Phillips, Canada

    4. The Use of Ketamine in Clinical Practice: Data Set From 6,000 Community Patients
    Steve Levine, United States
    Symposium

  • Chair: Anthony Grace, United States and Chih-Ken Chen, Taiwan

    1. Cannabis-Associated Psychosis; Mechanisms and Implications
    Robin Murray, United Kingdom

    2. The Neuroimmune Hypothesis of Schizophrenia and Cannabis Use Relevance in Youth - Novel Studies with TSPO PET
    Romina Mizrahi, Canada

    3. Inability to Regulate Stress Prepubertally as a Risk Factor for Schizphrenia: Disregulation of Prefrontal-Amygdala-Hippocampal Circuitry
    Anthony Grace, United States

    4. A Convergent Circuit for Genetic and Environmental Risk for Schizophrenia
    Andreas Meyer-Lindenberg, Germany
    Symposium

  • Chair: Elias Eriksson, Sweden and Pierre Blier, Canada

    Neurobiological and Physiological Consequences of Social Isolation: A Portal to Psychopathology
    Maria Oquendo, University of Pennsylvania, United States
    Plenary Lecture

  • Chair: Kazutaka Ikeda, Japan and Susan Gau, Taiwan

    Transgenerational Epigenetics: A Key to Understand Neurodevelopmental Diseases
    Noriko Osumi, Tohoku University, Japan
    Plenary Lecture

  • Behaviour Addiction: Gaming Disorder and Internet Addiction, 行為成癮:電玩與網路成癮
    Chair: Tso-Jen Wang, Taiwan

    1. Psychiatric Comorbidities in Internet Gaming Disorder
    Chih-Hung Ko, Taiwan

    2. The Treatment of Internet Addiction/Internet Gaming Disorder in Children and Young Adults: An Update Meta-Analysis
    Ruu-Feng Tzang, Taiwan

    3. Collaboration of Intervention Strategies for Gaming Disorder and Internet Addiction
    Tso-Jen Wang, Taiwan

    4. Comprehensive Neuropsychotherapy Model for Internet Addiction-Based on Empirical Data from Brain Waves
    Nai-Wen Guo, Taiwan
    Mandarin Session

  • Chair: John Krystal, USA and Ming-Chyi Huang, Taiwan

    Konstantinos Fountoulakis, Greece:
    Continuous Adequate Treatment with Antipsychotics is the Only Long Term Option for Schizophrenia
    vs.
    Robin Murray, United Kingdom:
    Psychiatrists should be much more cautious about long-term prophylactic antipsychotics
    Debate

  • Chair: Mark Weiser, Israel and Chia-Yih Liu, Taiwan

    1. Aromatase in the Brain and Human Personality
    Kayo Takahasi, Japan

    2. Circuit and Cellular Substrates of the Differential Behavioral Response to Ovarian Steroids in Women with Reproductive Endocrine-Related Mood Disorders
    Peter Schmidt, United States

    3. Prenatal Steroid Hormones and Autistic Traits in Expectant Mothers and Their Children
    Alexandros Tsompanidis, United Kingdom

    4. Effect of Adjunctive Estradiol on Schizophrenia Among Women of Childbearing Age: A Randomized Controlled Trial
    Mark Weiser, Israel
    Symposium

  • Chair: Kenji Hashimoto, Japan and Susan Gau, Taiwan

    1. Antidepressant Effects and Mechanisms of Prefrontal Theta Burst Stimulation (TBS): A Ketamine-Responsive Animal Model of SSRI-Resistant Depression
    Cheng-Ta Li, Taiwan

    2. Major Depressive Disorder, Bone, and Ketamine
    Kai Zhang, China

    3. Molecular Mechanisms Underlying Rapid-Acting and Long-Lasting Antidepressant Effects of Ketamine
    Kenji Hashimoto, Japan

    4. Intravenous Arketamine for Treatment-Resistant Depression
    Lucas de Castro Quarantini, Brazil
    Symposium

  • Pharmacokinetics and Pharmacogenetics in Antipsychotics, 抗精神病劑之藥物動力學與藥物基因學
    Chair: Chuan-Yue Wang, China

    1. Two Novel Loci of RELN Associated with Antipsychotics Response & The Mechanism of TNIK Influence Antipsychotics Response Through Wnt Signaling Pathway
    Qingqing Xu, China

    2. A Rational Use of Clozapine Based on the Factors which Influence Clozapine Levels
    Chuan-Yue Wang and Can-Jun Ruan, China

    3. Ethnic Difference in Pharmacokinetic of Antipsychotics
    Shih-Ku Lin, Taiwan
    Mandarin Session

  • Cognitive and Behavioral Impairment in The Elderly: Clinical Manifestations and Potential Interventions, 老年人的認知和行為障礙:臨床表徵與潛在介入
    Chair: Tzung-Jeng Hwang, Taiwan

    1. Mild Behavioral Impairment and Its Treatment Consideration
    Cheng-Sheng Chen, Taiwan

    2. Effects of N-3 Polyunsaturated Fatty Acid Supplementation on Recurrence Prevention and Cognitive Function in Patients with Late-Life Depression
    Chih-Chiang Chiu, Taiwan

    3. The Role of Pro-Inflammatory Cytokines in Elderly Depression and Dementia and Potential Interventions
    Roger Ho Chun Man, Singapore

    4. New Considerations of the Treatment for Agitation in Dementia
    Tzung-Jeng Hwang, Taiwan
    Mandarin Session

  • Chair: Joseph Zohar, Israel and Naomi Fineberg, UK

    Effects of Cannabis in Adolescence and Depression Risk in Young Adulthood: From Animals to Human Studies
    Gabriella Gobbi, McGill University, Canada
    Plenary Lecture

  • Siegfried Kasper, Past CINP President, Austria and Pierre Blier, CINP President, Canada